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Last Updated: 02/06/19

Prostate SPOREs

Prostate cancer (PrCa) is the most commonly diagnosed cancer in men with the highest incidence in black men. In 2018 there was an estimated 164,690 new cases of PrCa and 29,430 deaths from this disease reported in the United States. The current prostate cancer SPOREs are highly collaborative translational research teams, sharing resources and conducting inter-institutional clinical studies for the prevention, monitoring, and treatment of PrCa. The SPOREs in PrCa play a central role in advancing translational cancer research with academia, industry, other government agencies, and the international research community. Translational research projects within the prostate SPORES explore the comprehensive landscape of PrCa research including impact of genetics involved in active surveillance, the molecular evolution of resistance to androgen deprivation therapies, cellular mechanisms involved in metastatic PrCa, targeting repair of DNA damage, blood biomarkers for risk stratification, the effect of diet on PrCa outcomes, and many more pioneering projects; all aimed at bringing targeted therapies to clinical trials.