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Translational Research Program (TRP)
Last Updated: 09/23/16

Prostate SPOREs

In 2016, it is estimated that over 180,000 new cases of prostate cancer and over 26,000 deaths from this disease will be reported in the United States. As part of an NCI-wide program aimed at identifying new opportunities in prostate cancer research, the NCI now supports eight SPOREs in prostate cancer. These SPOREs are highly collaborative translational research teams, sharing resources and conducting inter-institutional clinical studies for the prevention, monitoring, and treatment of prostate cancer. The SPOREs in prostate cancer play a central role in advancing translational cancer research with academia, industry, other government agencies, and the international research community.

The SPOREs in prostate cancer developed a number of new scientific approaches to address prostate cancer. Accomplishments include the development of a number of new model systems for preclinical studies of prostate cancer and making advances that have been accepted for clinical practice, such as the Partin tables for staging, the Kattan nomograms for prognosis, the adaptation of PSA dynamics as surrogate markers for survival, and the introduction of a number of novel serum and tissue markers for detection and diagnosis, including the molecular profiling of various stages of this disease. Seminal developments emerging from the Prostate SPOREs include the discovery of ETS family gene translocations in prostate cancer, the first common casual gene translocation to be identified in a major human solid tumor, and the development of new therapeutic modalities, such as second-generation antiandrogens, which are now prolonging the lives of many individuals with prostate cancer.

Dana-Farber Harvard Cancer Institute

Massimo Loda [Click Here]
Dana-Farber Cancer Institute
Medical Oncology
450 Brookline Ave. DA1537
Boston, MA 02215
Tel: (617) 632-4001
Fax: (617) 632-4005
Email: massimo_loda@dfci.harvard.edu

Steven Balk, MD, PhD
Professor of Medicine
Beth Israel Deaconess Medical Center
CLS Building Room 443
3 Blackfan Circle
Boston, MA 02215
Phone: (617) 735-2065
Fax: (617) 735-2050
Email: sbalk@bidmc.harvard.edu

For more information on this specific SPORE’s institution, please visit:
http://www.dfhcc.harvard.edu/spores/

Fred Hutchinson Cancer Research Center

Peter Nelson, MD [Click Here]
Fred Hutchinson Cancer Research Center
Division of Human Biology
1100 Fairview Avenue North, D4-100
PO Box 19024
Seattle, WA 98109-1024
Tel: (206) 667-3377
Fax: (206) 667-2917
Email: pnelson@fhcrc.org

For more information on this specific SPORE’s institution, please visit:
http://prostatespore.fhcrc.org/

Johns Hopkins University

William Nelson, MD, PhD [Click Here]
Department of Oncology
Johns Hopkins University School of Medicine
Blunting Blaustein Building, Room 151
1650 Orleans Street
Baltimore, MD 21231
Tel: (410) 614-1661
Fax: (410) 502-9817
Email: bnelson@jhmi.edu

For more information on this specific SPORE’s institution, please visit:
http://urology.jhu.edu/research/index.php

Memorial Sloan-Kettering Cancer Center

Howard Scher, MD [Click Here]
Chair, Urology Department
Memorial Sloan-Kettering Cancer Center
1275 York Avenue
New York, NY 10021
Tel: (212) 639-4322
Fax: (212) 422-1095
Email: scherh@mskcc.org

Northwestern University

William J. Catalona [Click Here]
Professor in Urology
Northwestern University
NMH/Galter Room 20-150
675 N. Saint Clair
Chicago, IL 60611
Phone: (312) 695-4471
Fax: (312) 695-7030
Email: wcatalona@nmff.org

For more information on this SPORE, please visit:
http://www.cancer.northwestern.edu/research/research_programs/spore/index.cfm

University of California, Los Angeles

Robert Reiter, MD, MBA [Click Here]
University of California, Los Angeles
Department of Urology
10833 Le Conte Ave, Box 951738
Los Angeles, CA 90095
Tel: (310) 794-7224
Fax: (310) 206-5343
Email: rreiter@mednet.ucla.edu

For more information on this specific SPORE’s institution, please visit:
http://urology.ucla.edu/body.cfm?id=229

University of Michigan

Arul Chinnaiyan, M.D., PhD [Click Here]
Professor, Department of Pathology and Urology
Director, Pathology Research Informatics
University of Michigan Medical Center
5316 CCGC, Box 0940
1400 East Medical Center Drive
Ann Arbor, MI 48109
Phone: (734) 615-4062
Fax: (734) 615-4498
Email: arul@umich.edu

For more information on this specific SPORE’s institution, please visit:
http://www.cancer.med.umich.edu/prostate-spore/index.html

University of Texas/MD Anderson

Christopher Logothetis, MD [Click Here]
Chairman and Professor
University of Texas
M. D. Anderson Cancer Center
Department of Genitourinary Medical Oncology
1515 Holocombe Boulevard
Houston, TX 77030
Tel: (713) 792-2830
Fax: (713) 745-7625
Email: clogothe@mdanderson.org

For more information on this specific SPORE’s institution, please visit:
https://www.mdanderson.org/research/departments-labs-institutes/spores/prostate-cancer-spore.html